教育背景

2011.9－2015.7   上海中医药大学   理学博士

2006.9－2009.6   第二军医大学     医学硕士

2002.9－2006.7   中国药科大学     理学学士

工作经历

2022.01-今            上海中医药大学中药研究所 研究员

2019.04–2021.12       上海中医药大学中药研究所 副研究员

2009.08–2019.03       第二军医大学第二附属医院 主管药师

围绕天然产物生物合成关键酶催化机理解析与设计，通过优质种质资源创新和合成生物学生产，推进中药资源可持续与品质提升。

2023年度上海市优秀学术带头人

2018年度上海市青年科技启明星

2021年“师风师德”优秀教师

2022年“师风师德”优秀教师

2023年“十大杰出青年”、“十大杏林精英”

教育部科技进步一等奖（2017，名列第3位）

上海药学科技奖一等奖（2024，名列第5位）

1. Zheng Zhou^#, Jingxian Feng^#, Juncheng Huo^#, Shi Qiu, Pan Zhang, Yun Wang, Qing Li, Yajing Li, Cuicui Han, Xiaobing Feng, Yonghao Duan, Ruibin Chen, Ying Xiao*, Ying He*, Lei Zhang*, Wansheng Chen*. Versatile CYP98A enzymes catalyze meta-hydroxylation reveals diversity of salvianolic acids biosynthesis. Plant Biotechnology Journal 2024. 22(6):1536-1548

2. Yuqi Qiao, Doudou Huang, Yajing Li, Songfan Jiang, Xiao Chen, Junfeng Chen, Ying Xiao*, Wansheng Chen*. Construction of lignan glycosides biosynthetic network in Escherichia coli using mutltienzyme modules. Microbial Cell Factories 2024, DOI: 10.1186/s12934-024-02467-1

3. Jingxian Feng^#, Yuan Yao^#, Yuqi Qiao^#, Xueqi Ma^#, Zongtai Wu, Yonghao Duan, Peng Di, Wansheng Chen*, Ying Xiao*. Effect of pinoresinol-lariciresinol reductases on biosynthesis of lignans with substrate selectivity in Schisandra chinensis. Phytochemistry 2024, 221: 114053.

4. Junfeng Chen^#, Yun Wang^#, Fengying Liang, Xun Zhou, Xiao Chen, Minghui Lu, Wei Sun, Qing Li, Yingbo Yang, Doudou Huang, Lei Zhang*, Ying Xiao*, Wansheng Chen*. IiUGT71B2 catalyzes lignan glycosylation in Isatis indigotica with substrates specificity. Industrial Crops and Products 2023, 195: 116483 

5. Junfeng Chen^#, Yun Wang^#, Peng Di^#, Shi Qiu, Zongyou Lv, Yuqi Qiao, Yajing Li, Jingfu Tan, Weixu Chen, Ma Yu, Ying Xiao*, Wansheng Chen*. Phenotyping of Salvia miltiorrhiza roots reveals associations between root traits and bioactive components. Plant Phenomics 2023，5：0098.

6. Jiaqi Yue, Ying Xiao*, Wansheng Chen*. Insights into genus Codonopsis: From past achievements to future perspectives. Critical Reviews in Analytical Chemistry 2023, 1-32. 

7. Ying Xiao^#, Guoning Zhang^#, Yingbo Yang^#, Jingxian Feng^#, Shi Qiu, Zhuzhen Han, Jiaran Geng, Wansheng Chen*. Molecular mechanism of acceptor selection in cyclodextrin glycosyltransferases catalyzed ginsenoside transglycosylation. Bioorganic Chemistry 2022, 128, 106094

8. Xiaoyi Shi^#, Jiaran Geng^#, Jingxian Feng^#, Yingbo Yang, Xueqi Ma, Wansheng Chen, Ying Xiao*. Identification and Investigation of a Novel NADP⁺-dependent Secoisolariciresinol Dehydrogenase from Isatis indigotica. Frontiers in Plant Science 2022, 13:1035121. 

9. Ying Xiao^#, Kai Shao^#, Jingwen Zhou^#, Lian Wang, Xueqi Ma, Di Wu, Yingbo Yang, Junfeng Chen, Jingxian Feng, Shi Qiu, Zongyou Lv, Lei Zhang*, Peng Zhang*, Wansheng Chen*. Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nature Communications 2021, 12:2828.

10. Ying Xiao^#, Jingxian Feng^#, Qing Li, Yangyun Zhou, Qitao Bu, Junhui Zhou, Hexin Tan, Yingbo Yang, Lei Zhang*, Wansheng Chen*. IiWRKY34 positively regulates yield, lignan biosynthesis and stress tolerance in Isatis indigotica. Acta Pharmaceutica Sinica B 2020, 10(12):2417-2432. 

1. 肖莹，冯婧娴，陈万生。IiWRKY34在调控菘蓝木脂素生物合成和抗逆胁迫反应中的应用。ZL201910421717.6

2. 肖莹，陈万生。IiPLR1氨基酸定点突变蛋白及其编码的基因和应用。ZL202010457692.8

3. 肖莹，张国宁，陈万生，杨颖博，冯婧娴，邱实。来源于环状芽孢杆菌的环糊精葡萄糖基转移酶的应用及人参皂苷类化合物糖基化方法。ZL 202111160937.1

4. 肖莹，马雪祺，陈万生，段永豪。五味子松脂醇-落叶松脂醇还原酶及其编码基因和应用。ZL 202210692604.1

5. 肖莹，李元玉，陈万生。菘蓝咖啡酸-O-甲基转移酶蛋白及其编码基因和应用。ZL 202111031460.7

6. 肖莹，王芸，陈军峰，邱实，陈万生。一种中药丹参品质评价方法及其应用。ZL 202110023273.8

先后主持科技部国家重点研发计划、国家自然科学基金面上项目、青年项目、上海市科委、教委等课题8项，并承担企业合作横向课题2项。

兼任世界中联中药分析专业委员会理事、上海市药学会生药专业委员会委员、《Medicinal Plant Biology》副主编、《Frontiers in Plant Science》副主编、《上海中医药大学学报》青年编委等。