• 邱实
    副研究员
    研究方向:中药化学、中药分析及中药质量控制研究
    邮箱:davidhugh@msn.cn
    职务:硕士生导师
    电话:021-51322403
    学历学位:博士

个人简历

教育背景

   

2013.09-2016.07   长春中医药大学     医学博士


2010.09-2013.07   长春中医药大学     理学硕士


2006.09-2010.07   天津中医药大学     理学学士

工作经历

   

2019.04-今       上海中医药大学中药研究所 副研究员,硕士生导师


2016.12–2016.12   美国密西西比大学国家天然产物中心,博士后


研究兴趣

中药成分新颖分析方法建立、中药质量评价及质量标准建立、植物代谢组分析、植物代谢生物学研究。


个人荣誉

   

2019年上海市浦江人才计划


2021年中国科协青年托举计划


获奖情况


2017年吉林省优秀博士论文


2018年全国中医药优秀博士论文


代表性论文

1. Jiadong Hu#, Shi Qiu#*, Feiyan Wang#, Qing Li#, Chunlei Xiang, Peng Di, Ziding Wu, Rui Jiang, Jinxing Li, Zhen Zeng, Jing Wang, Xingxing Wang, Yuchen Zhang, Shiyuan Fang, Yuqi Qiao, Jie Ding, Yun Jiang, Zhichao Xu*, Junfeng Chen*, Wansheng Chen*. Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia. Nature communications. 2023, 14, 4696.

2. Jingshi Xue#, Shi Qiu#, Xinlei Jia#, Jiani Chen, Zeshuai Lin, Jiawei Zhu, Xiaomeng Sun, Qianmin Gao, Xintao Chen, Chaowen Xi, Doudou Huang, Feng Zhang, Shouhong Gao, Zhipeng Wang, Jian Zhang, Xuan Liu, Guoliang Ren, Xia Tao*, Wansheng Chen*, Zhongnan Yang*, Stepwise changes in flavonoids in spores/pollen contributed to terrestrial adaptation of plants, Plant Physiology, 2023, kiad313.

3. Shiyuan Fang#, Shi Qiu#, Kaixian Chen, Zongyou Lv*, Wansheng Chen*, The transcription factors SbMYB45 and SbMYB86.1 regulate flavone biosynthesis in Scutellaria baicalensis, Plant Physiology and Biochemistry, 2023, 200, 107794.

4. Houshan Yao#, Huilin Xu#, Shi Qiu#, Jiani Chen, Zeshuai Lin, Jiawei Zhu, Xiaomeng Sun, Qianmin Gao, Xintao Chen, Chaowen Xi, Doudou Huang, Feng Zhang, Shouhong Gao, Zhipeng Wang, Jian Zhang, Xuan Liu, Guoliang Ren, Xia Tao*, Mingming Li*, Wansheng Chen*, Choline deficiency-related multi-omics characteristics are susceptible factors for chemotherapy-induced thrombocytopenia, Pharmacological Research, 2022, 178, 106155.

5. Doudou Huang#, Chen Zhang#, Junfeng Chen, Ying Xiao, Mingming Li, Lianna Sun, Shi Qiu*, Wansheng Chen*, Computational workflow to study the diversity of secondary metabolites in fourteen different Isatis species, Cells, 2022, 11, 907.

6. Lili Cui#, Zhipeng Wang#, Shi Qiu#, Mengwei Zhang, Yanping Liu, Fengjing Xu, Xinhua Song, Shouhong Gao*,Wansheng Chen*, LC-MS/MS method for determination of hydroxychloroquine and metabolites: application in a pharmacokinetic study, Journal of Analytical Methods in Chemistry, 2022, 10, 1155.

7. Qi Tong#, Chen Zhang#, Yan Tu, Junfeng Chen, Qing Li, Zhen Zeng, Feiyan Wang, Lianna Sun, Doudou Huang, Mingming Li, Shi Qiu*, Wansheng Chen*, Biosynthesis-based spatial metabolome of Salvia miltiorrhiza Bunge by combining metabolomics approaches with mass spectrometry-imaging, Talanta, 2022, 238, 123045.

8. Shi Qiu#, Yan Tu#, Doudou Huang, Zhiying Dong, Mengqiu Huang, Jiaxi Cheng, Jingfu Tan, Weixu Chen, Lianna Sun*, Wansheng Chen*, Selection of appropriate post-harvest processing methods based on the metabolomics analysis of Salvia miltiorrhiza Bunge, Food Research International, 2021, 144, 110366.

9. Cuiyun Huang#, Shi Qiu#, Xiangcheng Fan#, Guangyang Jiao, Xun Zhou, Mei Sun, Nan Weng, Shouhong Gao, Xia Tao, Feng Zhang*, Wansheng Chen*, Evaluation of the effect of Shengxian Decoction on doxorubicin-induced chronic heart failure model rats and a multicomponent comparative pharmacokinetic study after oral administration in normal and model rats, Biomedicine & Pharmacotherapy, 2021, 144, 112354.

10. Liang Wang#, Ying Ma#, Yuqiong He#, Jiuling Deng, Doudou Huang, Xiaoli Zhang, Kaixian Chen, Shi Qiu*, Wansheng Chen*, Systematic investigation of the pharmacological mechanism of Tanreqing injection in treating respiratory diseases by UHPLC/Q-TOF-MS/MS based on multiple in-house chemical libraries coupled with network pharmacology, Journal of Pharmaceutical and Biomedical Analysis, 2021, 202, 114141.

11. Jiuling, Deng#, Ying Ma#, Yuqiong He#, Hong Yang, Yanhong, Chen, Liang Wang, Doudou Huang, Shi Qiu*, Xia Tao*, Wansheng Chen*, A network pharmacology-based investigation to the pharmacodynamics material basis and mechanisms of the anti-inflammatory and anti-viral effect of Isatis indigotica, Drug Design, Development and Therapy, 2021, 15, 3193-3206.

12. Shi Qiu, Shabana I. Khan, Mei Wang, Jianping Zhao, Siyu Ren, Ikhlas A. Khan, Amy Steffek, William P. Pfund, Xingcong Li*, Chemometrics-assisted identification of anti-inflammatory compounds from the green alga Klebsormidium flaccidum var. zivo, Molecules, 2020, 25, 1048.

13. Shi Qiu, Bharathi Avula, Shaohua Guan, Ranga Rao Ravu, Mei Wang, Jianping Zhao, Ikhlas A. Khan, Maud Hinchee, Xingcong Li*, Identification of fusaricidins from the antifungal microbial strain Paenibacillus sp. MS2379 using ultra-high performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, Journal of Chromatography A, 2019, 1586, 91-100. 


授权专利



科研项目

先后主持国家自然基金青年基金、中国科协青年托举计划、上海市浦江人才计划上海市科委科技创新行动计划、国家重点实验室开放课题等8项。


学术任职

中华中医药学会委员。