个人简历
教育背景
2022.11-2023.09 加拿大麦吉尔大学 客座教授
2015.04-2017.04 阿拉巴马大学伯明翰分校 博士后
2010.09-2014.12 上海交通大学Bio-X 研究院 理学博士
2003.09-2006.07 中国农业科学院研究生院 理学硕士
1999.09-2003.07 山东农业大学 理学学士
工作经历
2019.09-今 上海中医药大学中药研究所 副研究员,研究生生导师
2017.05-2019.09 中国科学院上海生命科学研究院马普计算生物研究所 副研究员
2008.01-2010.09 上海创翼生物科技有限公司 项目部经理
2006.10-2008.01 上海吉玛生物制药有限公司 项目经理
研究兴趣
探讨基因和环境的相互作用引起的各种表观遗传形式的改变及其相关的分子机制;探讨治疗精神分裂症、抑郁症、新型冠状病毒等复杂疾病的有效天然产物的发现及筛选;临床数据、疾病相关的多组学数据以及药物相关的建模以及数据分析。
个人荣誉
获奖情况
代表性论文
1.Han M, Yuan L, Gan S, Huang Y, Yan Y, Du C*, Wang Q*, Zhang G* Co-expression network analysis integrated in major depressive disorder and bipolar disorder discovers novel tissue-specific risk genes in mood disorders. Frontier in Psychiatry. 2022 August 23 doi:10.3389/fpsyt.2022.980315
2.Lei C, Wang Q*. The Progression of N6-methyladenosine Study and Its Role in Neuropsychiatric Disorders. Int J Mol Sci. 2022 May 25;23(11):5922. doi: 10.3390/ijms23115922.
3.Liao Q, Chen Z, Tao Y, Zhang B, Wu X, Yang L*, Wang Q *, Wang Z. An integrated method for optimized identification of effective natural inhibitors against SARS-CoV-2 3CLpro. Sci Rep. 2021 Nov 23;11(1):22796.
4.Wang Q, Dwivedi Y. Advances in novel molecular targets for antidepressants. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Jan 10;104:110041. doi: 10.1016/j.pnpbp.2020.110041.
5.Wang H, Deng Y, Peng S, Yan L, Xu H, Wang Q*, Shen Z. RNA-Seq based transcriptome analysis in oral lichen planus. Hereditas. 2021 Oct 6;158(1):39.
6.Li J, Niu X, Si Q, Song Q, Jin M, Zhou R, Sun Y, Li J, Wang Q*. Plasma periostin as a biomarker of osteoporosis in postmenopausal women with type 2 diabetes. J Bone Miner Metab. 2021 Jul;39(4):631-638. doi: 10.1007/s00774-020-01200-3. Epub 2021 Feb 10.
7.Chen Y, Wang H, Jiang Y, Zhang X, Wang Q*. Transcriptional profiling to identify the key genes and pathways of pterygium. PeerJ. 2020 May 4;8:e9056. doi: 10.7717/peerj.9056. eCollection 2020.
8. Zhou C, Xu Q, He S, Ye W, Cao R, Wang P, Ling Y, Yan X, Wang Q, Zhang G. GTDB: an integrated resource for glycosyltransferase sequences and annotations. Database (Oxford). 2020 Jan 1;2020:baaa047. doi: 10.1093/database/baaa047.
9.CNCB-NGDC Members and Partners. Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021. Nucleic Acids Res. 2021 Jan 8;49(D1):D18-D28. doi: 10.1093/nar/gkaa102.
10. Wang Q, Roy B, Dwivedi Y. Co-expression network modeling identifies key long non-coding RNA and mRNA modules in altering molecular phenotype to develop stress-induced depression in rats. Transl Psychiatry. 2019 Apr 3;9(1):125. doi: 10.1038/s41398-019-0448-z.
11. Geng R, Li Z, Yu S, Yuan C, Hong W, Wang Z, Wang Q*, Yi Z, Fang Y. Weighted gene co-expression network analysis identifies specific modules and hub genes related to subsyndromal symptomatic depression. World J Biol Psychiatry. 2020 Feb;21(2):102-110. doi: 10.1080/15622975.2018.1548782. Epub 2019 Jan 8.
12. Li J, Niu X, Li J, Wang Q*. Association of PPARG Gene Polymorphisms Pro12Ala with Type 2 Diabetes Mellitus: A Meta-analysis. Curr Diabetes Rev. 2019;15(4):277-283. doi: 10.2174/1573399814666180912130401.
授权专利
科研项目
先后主持国家自然科学基金面上项目、上海市卫计委等多个研究项目
课题组成员
雷春光 (2020级硕士研究生)
彭思琦(2020级硕士研究生)
周亚兰 (2021级硕士研究生)
王慧珍 (2022级硕士研究生)