教育背景

2020.09－2021.09    伦敦国王学院  情绪障碍   理学硕士

2012.09－2015.07    上海中医药大学  中药学     理学博士

2008.09－2011.07    南昌大学医学院   临床药理   医学硕士

2004.09－2008.07    南昌大学医学院   临床药学   理学学士

工作经历

2018.01-今        上海中医药大学中药研究所 副研究员，硕士生导师

2019.11-今        伦敦国王学院精神-心理-神经科学研究所 访问学者

2015.10–2017.12   上海中医药大学中药研究所 助理研究员

2015.07-2017.07   上海中医药大学中药研究所 师资博士后

2011.07–2012.07   上海长海医院药学部主任秘书、临床试验质控员

中药及其活性成分在应激所致的神经精神疾病、心身疾病中的作用和机制研究

个人荣誉

2017年度上海市青年科技英才扬帆计划

1. Tao Y^#, Zhou H^#, Li Z, Wu H, Wu F, Miao Z, Shi H, Huang F*, Wu X*. TGR5 deficiency-induced anxiety and depression-like behaviors: The role of gut microbiota dysbiosis. J Affect Disord. 2024 Jan 1; 344: 219-232.

2. Tao Y^#, Shen W^#, Zhou H, Li Z, Pi T, Wu H, Shi H, Huang F*, Wu X*. Sex differences in a corticosterone-induced depression model in mice: Behavioral, neurochemical, and molecular insights. Brain Res. 2023 Nov 17; 1823: 148678.

3. Huang F, Mariani N, Pariante CM, Borsini A*. From dried bear bile to molecular investigation of differential effects of bile acids in ex vivo and in vitro models of myocardial dysfunction: Relevance for neuroinflammation. Brain Behav Immun Health. 2023 Aug 2; 32: 100674.

4. Shen W^#, Tao Y^#, Zheng F, Zhou H, Wu H, Shi H, Huang F*, Wu X*. The alteration of gut microbiota in venlafaxine-ameliorated chronic unpredictable mild stress-induced depression in mice. Behav Brain Res. 2023 May 28;446:114399.

5. Bai Y^#, Zhou J^#, Zhu H, Tao Y, Wang L, Yang L, Wu H, Huang F*, Shi H, Wu X*. Isoliquiritigenin inhibits microglia-mediated neuroinflammation in models of Parkinson's disease via JNK/AKT/NFκB signaling pathway. Phytother Res. 2023 Mar;37(3):848-859.

6. Zhu H, Bai Y, Wang G, Su Y, Tao Y, Wang L, Yang L, Wu H, Huang F*, Shi H, Wu X*. Hyodeoxycholic acid inhibits lipopolysaccharide-induced microglia inflammatory responses through regulating TGR5/AKT/NF-κB signaling pathway. J Psychopharmacol. 2022 Jul; 36(7): 849-859.

7. Zhu H^#, Wang G^#, Bai Y, Tao Y, Wang L, Yang L, Wu H, Huang F*, Shi H, Wu X*. Natural bear bile powder suppresses neuroinflammation in lipopolysaccharide-treated mice via regulating TGR5/AKT/NF-κB signaling pathway. J Ethnopharmacol. 2022 May 10; 289:115063.

8. Huang F, Pariante CM, Borsini A*. From dried bear bile to molecular investigation: A systematic review of the effect of bile acids on cell apoptosis, oxidative stress and inflammation in the brain, across pre-clinical models of neurological, neurodegenerative and neuropsychiatric disorders. Brain Behav Immun. 2022 Jan; 99:132-146.  

9. Huang F. Ursodeoxycholic acid as a potential alternative therapeutic approach for neurodegenerative disorders: Effects on cell apoptosis, oxidative stress and inflammation in the brain. Brain Behav Immun Health. 2021; 18:100348.

10. Tao Y, Zheng F, Cui D, Huang F*, Wu X*. A combination of three plasma bile acids as a putative biomarker for schizophrenia. Acta Neuropsychiatr. 2021;33(1): 51-54.

11. Huang F, Wu X*. Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression. Front Cell Dev Biol. 2021 Mar 11; 9: 649103.  

1. 吴晓俊, 王峥涛, 黄菲, 郑方, 周强. 胆汁酸成分及熊胆的医药用途. ZL 201610131100.7

2. 吴晓俊, 王峥涛, 胡之璧，黄菲. 黄芪甲苷的医药用途. ZL 201310240120.4

3. 吴晓俊, 王峥涛, 胡之璧，黄菲. 黄芪总皂苷的医药用途. ZL 201310250408.X

先后主持科技部国家自然基金青年项目、上海市科委上海市自然科学基金、上海市青年科技英才扬帆计划、上海市卫健委临床专项、上海市教委预算内项目等6余项。

兼任上海市中西医结合学会神经内分泌专委会委员，英国精神药理学联盟青年会员，国际心理神经内分泌学会青年会员等。