教育背景

2018.09 - 2022.12    上海中医药大学   博士

2012.09 - 2015.07    北京中医药大学   硕士

2008.09 - 2012.07    广东药学院       学士

工作经历

2024.01 - 至今      上海中医药大学中药研究所   高级实验师

2019.01 - 2023.12    上海中医药大学中药研究所   实验师

2015.08 - 2018.12    上海中医药大学中药研究所   助理实验师

聚焦中药活性成分的吸收、分布、体内外代谢特征、色谱-质谱分析技术开发与应用，为中药药效物质基础研究、中药制剂与质量控制研究奠定基础。

个人荣誉

无

获奖情况

2024年中国民族医药协会科学技术奖（排名12）

[1] Dang R, Xie Z, Cai F, Sun X, Fang Q, Wang G, Guan H*, Wang C*. Revealing the mechanism of Sanfu Patch dorsal application for alleviating OVA-induced asthma: an integrated approach combining TMT quantitative proteomics and molecular docking. J Ethnopharmacol. 2025; 348: 119867.

[2] Bahatijiang M, Xu N, Hu X, Liu W, Lei J, Zhang S, Cai F, Xie Z, Zhou M, Wang J, Gao H, Teng L*, Guan H*, Wang C*. Simultaneous Quantification of a Novel β-Carboline Alkaloid Derivative and Its Three Metabolites in Rat Plasma by UHPLC-MS/MS and Its Application to a Pharmacokinetic Study. J Sep Sci. 2025, (9): e70282.

[3] Wang X, Zhang L, Gao X, Zhang L, Yu J, Liu Y, Fang M, Yan Y, Chen L, Du J, Guan H*, Huang C*, Fan S*. Liu Jun Zi Decoction extends lifespan and healthspan through p16/p21 signaling in Caenorhabditis elegans. Biogerontology. 2025;26(6):201.

[4] Guan H, Chen J, Yin H, Feng X, Liu C, Liu S, Li J, Li J, Cao Y*, Ma C*. A UHPLC-MS/MS Method Reveals the Pharmacokinetics of Deacetyl Asperulosidic Acid Methyl Ester in Rats. Biomed Chromatogr. 2025; 39(3):e70001.

[5] 党蕊, 管辉达*, 王长虹*. 三伏贴凝胶膏剂制备工艺与体外透皮特性研究[J].中草药,2025,56(13):4608-4620.

[6] Xiang Z, Guan H, Xie Q, Hu X, Liu W, Zhang S, Chen Q, Lei J, Shen Q, Liu W, Li M*, Wang C*. Exploring the tissue distribution propensity of active alkaloids in normal and stomach heat syndrome rats following oral administration of Zuojin Pill based on pharmacokinetics and mass spectrometry imaging. J Ethnopharmacol. 2025; 346:119627.

[7] Xiang Z, Guan H, Zhao X, Xie Q, Hu X, Liu W, Sun X, Zhang S, Li M*, Wang C*. Characterization of active alkaloids and metabolites in rats after oral administration of Zuojin Pill using UHPLC-Q-TOF-MS combined with bioinformatics and molecular docking analyses. J Pharm Biomed Anal. 2024; 249:116340.

[8] Xiang Z, Guan H, Zhao X, Xie Q, Cai F, Xie Z, Dang R, Li M*, Wang C*. Protoberberine alkaloids: A review of the gastroprotective effects, pharmacokinetics, and toxicity. Phytomedicine. 2024; 126:155444.

[9] Dang R1, Guan H1, Wang C*. Sinapis Semen: A review on phytochemistry, pharmacology, toxicity, analytical methods and pharmacokinetics. Front Pharmacol. 2023; 14:1113583.

[10] Ding Y1, Guan H1, Yan Y, Chen Y, Huang C*. Pharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice. Heliyon. 2023; 9(11): e22016.

主持国家自然科学基金青年基金1项，上海中医药大学科技发展项目2项，作为主要参与者参与国家自然科学基金面上基金、国家重点研发计划及上海市科委项目等多个研究项目。

兼任中国医药生物技术协会纳米生物技术分会委员，中华中医药学会、中国化学会等协会会员，西北药学杂志青年编委，J. Ethnopharmacol., J. Pharm. Biomed. Anal., J. Sep. Sci., Front. Pharmacol. 等期刊审稿人。