教育背景

2018.09－2024.07    上海中医药大学      理学博士

2010.09－2013.07    中国药科大学        理学硕士

2006.09－2010.07    福建师范大学         工学学士

工作经历

2026.01-今         上海中医药大学中药研究所 高级实验师，硕士生导师

20017.01－2025.12   上海中医药大学中药研究所   实验师

2013.08-2016.12    上海中医药大学中药研究所  助理实验师

中药复方及其天然活性单体在中枢神经炎症相关疾病（帕金森病）、自身免疫神经退行性疾病（多发性硬化症）中的分子作用通路、药效物质基础及疾病治疗潜在靶点筛选研究。

2017年上海中医药大学杏林青年学者

获奖情况

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1. Jinfeng Yuan, Yanlin Tao, Mengxue Wang, Yufeng Chen, Xinyan Han, Hui Wu*, Hailian Shi, Fei Huang, Xiaojun Wu*. Astragaloside II, a natural saponin, facilitates remyelination in demyelination neurological diseases via p75NTR receptor mediated β-catenin/Id2/MBP signaling axis in oligodendrocyte precursor cells. J Adv Res, 2026, 80: 577-591.

2. Chenyang Ni#, Lupeng Wang#, Yuyan Bai, Fei Huang, Hailian Shi, Hui Wu*, Xiaojun Wu*, Jin Huang*. Taurochenodeoxycholic acid activates autophagy and suppresses inflammatory responses in microglia of MPTP-induced Parkinson’s disease mice via AMPK/mTOR, AKT/NFκB and Pink1/Parkin signaling pathways mediated by Takeda G protein-coupled receptor 5. Free Rad Biol Med, 2025, Aug 1, 235: 347-363.

3. Yingying Song#, Xiaojuan Zhang#, Xinyan Han, Gaorui Wang, Mengxue Wang, Hui Wu*, Xiaojun Wu*. Ginsenoside Rb1 alleviates blood-brain barrier damage and demyelination in experimental autoimmune encephalomyelitis mice by regulating JNK/ERK/NF-κB signaling pathway. J Ethnopharmcol, 2025, 343:119448.

4. Hui Wu, Chenyang Ni, Yu Zhang, Yingying Song, Longchan Liu, Fei Huang*, Hailian Shi, Zhengtao Wang, Xiaojun Wu*. Stem-leaf saponins of Panax notoginseng attenuate experimental Parkinson's disease progression in mice by inhibiting microglia-mediated neuroinflammation via P2Y2R/PI3K/AKT/NFκB signaling pathway. Chin J Nat Med, 2025, 23(1):43-53.

5. Nuo Xu#, Yuyan Bai#, Xinyan Han, Jinfeng Yuan, Lupeng Wang, Yixin He, Liu Yang, Hui Wu*, Hailian Shi, Xiaojun Wu*. Taurochenodeoxycholic acid reduces astrocytic neuroinflammation and alleviates experimental autoimmune encephalomyelitis in mice. Immunobiology, 2023, 228: 152388.

6. Hui Wu , Gaorui Wang , Xinting Wang , Yuyan Bai, Jinfeng Yuan , Liu Yang , Fei Huang , Hailian Shi , Xiaojun Wu*. Astragaloside IV ameliorates metabolic disorder in db/db obese mice as a PPARγ antagonist. J Asian Nat Prod Res, 2023, 25(5):484-496

1. 吴晓俊，王峥涛，曹秦，秦立悦，吴辉，石海莲，张蓓蓓。紫檀烷苷的医药用途，ZL201410838023.X

主持上海市自然科学基金面上项目1项，上海中医药大学科技发展项目2项，作为主要参与者参与国家自然科学基金面上基金、国家重点研发计划及上海市科委项目等多个研究项目。

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